Relationship Between Neutrophil-Lymphocyte Ratio Value And Severity of Mitral Stenosis Due to Rheumatic Heart Disease in Outpatients at H. Adam Malik General Hospital Medan
Authors
Abstract
Introduction: Mitral stenosis (MS) is a heart valve disease characterized by narrowing of the mitral valve, commonly caused by rheumatic heart disease. Accurate evaluation of MS severity is crucial for management, with echocardiography being the gold standard. The Neutrophil-Lymphocyte Ratio (NLR), reflecting inflammation, may correlate with MS severity. This study aims to assess the relationship between NLR values and MS severity due to rheumatic heart disease.
Method: This cross-sectional study was conducted at H. Adam Malik General Hospital Medan from January 2023 until the required sample size was achieved. Patients diagnosed with MS by echocardiography based on the American Society of Echocardiography (ASE) criteria were included. Echocardiographic parameters such as mitral valve area (MVA) and mean pressure gradient (MV mean PG), along with blood NLR values, were analyzed for associations. Statistical significance was set at P < 0.05.
Results: Significant differences in NLR values were observed between mild-to-moderate MS (1.93; 0.82–10.64) and severe MS (3.56; 1.81–13.08) (P = 0.0001, Mann-Whitney test). An NLR threshold of 2.91 predicted severe MS with 82% sensitivity and 81.8% specificity (P = 0.0001; AUC 0.856; 95% CI 0.772–0.940).
Conclusion: NLR strongly correlates with MS severity and serves as a reliable predictor for severe MS in patients with rheumatic heart disease. NLR offers a simple, cost-effective tool for assessing MS severity, complementing echocardiography in clinical practice.
Similar Articles
- Rina Sari Mardia, Bintang YM Sinaga, Parluhutan Siagian, Ashar Taufik, Characteristics of Loss to Follow-Up Patient in Drug-Sensitive Pulmonary TB in Medan , Journal of Society Medicine: Vol. 3 No. 10 (2024): Oktober
- Primta Bangun, Suwarman Suwarman, Weaning Difficulty in Patient with End Stage Renal Disease Acute with Respiratory Failure due to Pulmonary Edema and Pneumonia , Journal of Society Medicine: Vol. 2 No. 2 (2023): February
- Al-Ma’ Arij Akbar Lubis, Cut Aryfa Andra, Andre Pasha Ketaren, Relationship between QTc interval prolongation and mortality of acute ischaemic stroke patients during treatment and three months after treatment at Adam Malik Hospital , Journal of Society Medicine: Vol. 3 No. 3 (2024): March
- Rendi Sidiq, Bastian Lubis, Yutu Solihat, Comparison of Pre-Loading Fluid With Norepinephrine Toward Mean Arterial Pressure (MAP) In Sepsis Patients In Intensive Care Unit (ICU) of Haji Adam Malik General Hospital, Medan , Journal of Society Medicine: Vol. 1 No. 2 (2022): November
- M Yusuf Adira Putra, Amira Permatasari Tarigan, Andika Pradana, Riska Resti, Adini Arifah Ramadhani, Syafiah Amalina Nasution, A Study of Relationship Between Asthma Control Test, Lung Function, & Hospitalization , Journal of Society Medicine: Vol. 3 No. 12 (2024): December
- Mirton, Pasihulilzan, Hesty Rhauda Ashan, Performed Laparoscopic Surgery For Gastric Perforation: Case Report , Journal of Society Medicine: Vol. 3 No. 6 (2024): June
- Mustaqin Mustaqin, Niken Asri Utami, Tgk. Puspa Dewi, Bayu Azizka Putra Fandika, Dandy Walker Malformation Prenatal Diagnosis and Postnatal Outcome in Multigravida: A rare Case , Journal of Society Medicine: Vol. 4 No. 6 (2025): June
- Ongta Gibson Sirait, Wulan Fadinie, Catecholamine Toxicity After Craniotomy Evacuation Craniotomy and Evacuation of The Abscess , Journal of Society Medicine: Vol. 1 No. 2 (2022): November
- Batian Lubis, Dis Bima P Purwaamidjaja, Mayang Indah Lestari, Faisal, Muhammad Husni Thamrin, Febri Akhmad Belinda, A Case Series of Bleeding Complication Post Percutaneous Dilatational Tracheostomy and Management , Journal of Society Medicine: Vol. 2 No. 12 (2023): December
- M. Rizky Priyanka Asepty, Anggia Chairuddin Lubis, Zulfikli Mukhtar, Predictors of Success of Ablation Procedures in Patients with Non-Structural Premature Ventricular Contraction at Adam Malik Hospital , Journal of Society Medicine: Vol. 3 No. 9 (2024): September
You may also start an advanced similarity search for this article.