Correlation between Glycated Hemoglobin and Calcium Levels in Pediatric with Type 1 Diabetes Mellitus

Indah Nasution; Karina Sugih Arto; Bugis Mardina Lubis

doi:10.47353/jsocmed.v2i11.101

Correlation between Glycated Hemoglobin and Calcium Levels in Pediatric with Type 1 Diabetes Mellitus

Indah Nasution
Resident Department of Pediatrics, Faculty of Medicine, Universitas Sumatera Utara, Medan, North Sumatra, Indonesia
Karina Sugih Arto
Department of Pediatrics, Faculty of Medicine, Universitas Sumatera Utara, Medan, North Sumatra, Indonesia
Bugis Mardina Lubis
Department of Pediatrics, Faculty of Medicine, Universitas Sumatera Utara, Medan, North Sumatra, Indonesia

Abstract

Introduction: Type 1 diabetes mellitus is a systemic disorder resulting from impaired glucose metabolism characterized by chronic hyperglycemia. Caused by damage to pancreatic β cells either by autoimmune or idiopathic processes resulting in reduced or even halted insulin production. Diabetes mellitus is associated with a decrease in calcium with impaired intestinal calcium absorption and hypercalciuria which causes a decrease in calcium absorption into the body.

Method: This study used a prospective study method to assess the correlation between HbA1C levels and calcium levels in children with type 1 diabetes mellitus. This research was conducted in the Endocrinology Outpatient Unit of Haji Adam Malik Hospital Medan, May 2022 to December 2022. The samples were children aged 1 month to 18 years.

Results: Correlation is measured using Pearson correlation analysis for normally distributed data while Spearman correlation is used for data that was not normally distributed. There is a significant correlation between the HbA1c and calcium levels with a p value of 0.026 and a correlation value of (r= -0.445). The correlation value is negative, meaning that every increase in HbA1c levels will be followed by a decrease in serum calcium levels in children with type I diabetes, with moderate strength (r= 0.4 – 0.6). This effect is not influenced by diseases duration and onset of diabetes.

Conclusion: There is a decrease in calcium in type 1 diabetes

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Published at

30. November 2023
https://doi.org/10.47353/jsocmed.v2i11.101
Issue:

Vol. 2 No. 11 (2023): November
Section:

Articles
Keywords:

Diabetes mellitus type 1 HbA1c Calcium Pediatric
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Nasution, I., Arto, K. S., & Lubis, B. M. (2023). Correlation between Glycated Hemoglobin and Calcium Levels in Pediatric with Type 1 Diabetes Mellitus. Journal of Society Medicine, 2(11), 377–383. https://doi.org/10.47353/jsocmed.v2i11.101