Correlation of Fibrinogen Level with PELOD-2 Score As A Predictive Factor For Mortality in Pediatric Sepsis

Dia Tri Susanti; Gema Nazri Yanni; Johannes H. Saing; Erna Mutiara; Aridamuriany D. Lubis; Olga R. Siregar

doi:10.47353/jsocmed.v2i11.106

Correlation of Fibrinogen Level with PELOD-2 Score As A Predictive Factor For Mortality in Pediatric Sepsis

Dia Tri Susanti
Department of Pediatrics, Faculty of Medicine, Universitas Sumatera Utara, Medan, North Sumatra, Indonesia
Gema Nazri Yanni
Department of Pediatrics, Faculty of Medicine, Universitas Sumatera Utara, Medan, North Sumatra, Indonesia
Johannes H. Saing
Department of Pediatrics, Faculty of Medicine, Universitas Sumatera Utara, Medan, North Sumatra, Indonesia
Erna Mutiara
Faculty of Public Health, Universitas Sumatera Utara, Indonesia
Aridamuriany D. Lubis
Department of Pediatrics, Faculty of Medicine, Universitas Sumatera Utara, Medan, North Sumatra, Indonesia
Olga R. Siregar
Department of Pediatrics, Faculty of Medicine, Universitas Sumatera Utara, Medan, North Sumatra, Indonesia

Abstract

Introduction: Fibrinogen is a prognostic biomarker in septic children, lower fibrinogen levels are closely related to higher risk of death. Organ dysfunction was diagnosed based on PELOD-2 score. The aim of this study was to determine the corelation between fibrinogen levels and PELOD-2 score as a predictor of mortality in pediatric patient with sepsis treated in the PICU and HCU at H. Adam Malik General Hospital.

Method: A cross-sectional study of pediatric patients with sepsis treated in the PICU and HCU H. Adam Malik General Hospital, Medan. Correlation of fibrinogen levels with PELOD-2 scores was seen on day I and day III of treatment in patient aged 1 month to 18 years with a hospital stay of at least 72 hours and were analyzed using the Spearman test and the relationship between fibrinogen and mortality was analyzed using the Mann-Whitney test.

Results: 50 subjects were recruited in this study, fibrinogen levels had no correlation with PELOD-2 score day I (p = 0,074, r = -0,225) and with PELOD-2 score days III (p = 0,110, r = -0,229) and with mortality (p = 0,160).

Conclusion: Fibrinogen levels were not correlate with PELOD-2 score as a predictive factor for mortality in septic children.

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Published at

30. November 2023
https://doi.org/10.47353/jsocmed.v2i11.106
Issue:

Vol. 2 No. 11 (2023): November
Section:

Articles
Keywords:

Fibrinogen PELOD-2 score Mortality
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Susanti, D. T., Yanni, G. N., Saing, J. H., Mutiara, E., Lubis, A. D., & Siregar, O. R. (2023). Correlation of Fibrinogen Level with PELOD-2 Score As A Predictive Factor For Mortality in Pediatric Sepsis. Journal of Society Medicine, 2(11), 384–391. https://doi.org/10.47353/jsocmed.v2i11.106