The TIMI Risk Index as a Predictor of Contrast-Induced Nephropathy in Patients Undergoing Primary Percutaneous Coronary Intervention at Haji Adam Malik Hospital Medan
Authors
Abstract
Introduction: ST-segment elevation myocardial infarction (STEMI) is a severe cardiovascular condition requiring urgent treatment through Primary Percutaneous Coronary Intervention (PPCI). However, PPCI increases the risk of Contrast-Induced Nephropathy (CIN), a condition characterized by a significant rise in serum creatinine levels. To minimize the risk of CIN, identifying patients at high risk is essential. This study evaluates the TIMI Risk Index (TRI) as a predictor of CIN in STEMI patients undergoing PPCI at Haji Adam Malik Hospital, Medan.
Methods: This observational analytical study employed a cross-sectional design, focusing on STEMI patients with symptoms lasting less than 12 hours who underwent PPCI between January 2023 and December 2024. Participants were selected according to inclusion and exclusion criteria. Bivariate analysis was used, with the chi-square test for normally distributed data and the Fisher exact test for non-normally distributed data, with a significance level of p < 0.05.
Results: The results indicated that TRI effectively predicted CIN occurrence, with a p-value of 0.0001, an area under the curve (AUC) of 0.834, and a 95% confidence interval (CI) of 0.752–0.916. A TRI cut-off score of 23.47 demonstrated a sensitivity of 77.3%, specificity of 77%, a positive predictive value (PPV) of 47.05%, and a negative predictive value (NPV) of 91.8%.
Conclusion: In conclusion, the TRI with a cut-off score of 23.47 is a reliable tool for predicting CIN in STEMI patients undergoing PPCI, offering high sensitivity, specificity, and NPV, which can help improve clinical outcomes by identifying at-risk patients.
Similar Articles
- Rizka Farahin Assania, Elvita Rahmi Daulay, Refli Hasan, Association of Risk Factors for Coronary Artery Disease with The Incidence of Abdominal Aortic Calcification On Abdominal CT-Scan Imaging in H. Adam Malik General Hospital , Journal of Society Medicine: Vol. 2 No. 3 (2023): March
- Roni Abimanyu, Andre Pasha Ketaren, Ali Nafiah Nasution, Relationship Between Left Atrium Reservoir Strain and One-Year Mortality After Surgery in Patients with Severe Primary Mitral Regurgitation Undergoing Mitral Valve Replacement at Haji Adam Malik General Hospital, Medan , Journal of Society Medicine: Vol. 4 No. 2 (2025): February
- Batian Lubis, Dis Bima P Purwaamidjaja, Mayang Indah Lestari, Faisal, Muhammad Husni Thamrin, Febri Akhmad Belinda, A Case Series of Bleeding Complication Post Percutaneous Dilatational Tracheostomy and Management , Journal of Society Medicine: Vol. 2 No. 12 (2023): December
- Faisal Adam, Cut Aryfa Andra, Hilfan Ade Putra Lubis, The Relationship between Heart Rate Recovery and Rate Pressure Product on Coronary Lesion Severity Using Syntax Score in Stable Angina Pectoris Patients at Haji Adam Malik Hospital Medan , Journal of Society Medicine: Vol. 3 No. 7 (2024): July
- Ratna Mariana Tamba, Hilfan Ade Putra Lubis, Zulfikri Mukhtar, Andika Sitepu, Faisal Habib, Cut Aryfa Andra, T. Bob Haykal, The Relationship between Transient Ischemic Dilation (TID) and Severity of Coronary Artery Disease (CAD) in Patients with Chronic Coronary Syndrome (CCS) in Haji Adam Malik Medan, Indonesia , Journal of Society Medicine: Vol. 2 No. 9 (2023): September
- Nengah Darmawan, Amira Permatasari Tarigan, Andika Pradana, Relationship Between Asthma Therapy Types, Pulmonary Function, and Asthma Control in Primary Healthcare Facilities in Medan , Journal of Society Medicine: Vol. 4 No. 2 (2025): February
- Novrida Pratiwi Tarigan, Elvita Rahmi Daulay, Syafrizal Nasution, Renal Artery Caliber In Abdominal CT Scan With IV Contrast Based on Age and Gender , Journal of Society Medicine: Vol. 1 No. 3 (2022): December
- T. Rifqi Hashmi, Harris Hasan, Hilfan Ade Putra Lubis, The Relationship between LDL/ HDL Ratio and Coronary Lesion Severity Measured by Syntax Score in Patients with Non-Elevation Acute Myocardial Infarction at Hajj Adam Malik General Hospital, Medan , Journal of Society Medicine: Vol. 3 No. 5 (2024): May
- Khansa Salsabila, Puji Pinta Omas Sinurat, Irina Kemala Nasution, Association between Coagulation Profile and Platelet Lymphocyte Ratio with Karnofsky Performance Status Scale In Brain Tumor Patients , Journal of Society Medicine: Vol. 2 No. 5 (2023): May
- Arna Fransica, Osmond Muftilov Pison , Management of A Preeclampsia Patient with Diabetic Ketoacidosis and Acute Pulmonary Edema : A Case Report , Journal of Society Medicine: Vol. 4 No. 3 (2025): March
You may also start an advanced similarity search for this article.