The Association of Nutrition Status Towards The Outcome of Acute Ischemic Stroke Patients with Type-2 Diabetes Mellitus

Siti Alimahtun Sodiah Chaniago; Iskandar Nasution; Irina Kemala Nasution

doi:10.47353/jsocmed.v2i1.26

The Association of Nutrition Status Towards The Outcome of Acute Ischemic Stroke Patients with Type-2 Diabetes Mellitus

Siti Alimahtun Sodiah Chaniago
Resident of Neurology Department, Faculty of Medicine, University of North Sumatera / Haji Adam Malik General Hospital, Medan, Indonesia
Iskandar Nasution
Staff of Neurology Department, Faculty of Medicine, University of North Sumatera / Haji Adam Malik General Hospital, Medan, Indonesia
Irina Kemala Nasution
Staff of Neurology Department, Faculty of Medicine, University of North Sumatera / Haji Adam Malik General Hospital, Medan, Indonesia

Abstract

Introduction: Stroke is a sudden-onset neurologic deficit and having a type 2 diabetes increases the risk of stroke twice as much. In addition to affecting physical and mental abilities, stroke can also lead to a decline in nutritional status. Malnutrition is associated with poor functional outcomes in all stroke subtypes. The Controlling Nutritional Status (CONUT) score is an objective nutritional marker and could reflects malnutrition due to its comprehensive assessment of nutritional status. This study aims to find the association between nutritional status towards the outcome of acute ischemic stroke patients with type 2 diabetes.

Method: This was an observational analytic study with prospective cohort design using primary data collected consecutively from patients with both acute ischemic stroke and type 2 diabetes mellitus who were hospitalized in the Stroke Corner Room, Intensive Care Unit (ICU) and inpatient ward of Haji Adam Malik General Hospital who met the inclusion criteria. The nutritional statuses of patients were measured using the CONUT score and patients outcomes were measured by mRS score. Spearman correlation test was used to assess the association between nutritional status and outcome of acute ischemic stroke patients with type 2 diabetes mellitus.

Results: There were 43 patients who met the inclusion criteria where the majority of patients were male 22 people (51.2%), in the age group 51-65 years 23 people (53.5%) with a mean age of 57.93 + 10.01, was a housewife 15 people (34.9%) and Bataknese 27 people (62.8%). The majority of patients in this study

had mild malnutrition with a total of 15 people (34.9%) and a median CONUT score of 3 (0-11) and poor outcome as many as 29 people (67.4%) with mRS score median 4 (0-6). The result of Spearman correlation test showed a significant correlation between nutritional status and the outcome of acute ischemic stroke patients with type 2 diabetes mellitus with a moderate correlation.

Conclusion: There was a significant correlation between nutritional status and the outcome of acute ischemic stroke patients with type 2 diabetes mellitus with a moderate correlation

Similar Articles

Cindy Giovanni, Nurita Dian Kestriani Saragi Sitio, Role of Intravenous Immunoglobulin (IVIG) in Patients with Guillain Barre Syndrome with Severe Community Pneumonia in The Intensive Care Unit (ICU) , Journal of Society Medicine: Vol. 3 No. 3 (2024): March
Aris Darmoko, Nurita Dian Kestriani , Intensive Care Management of Non-Ischemic Dilated Cardiomyopathy with Morbid Obesity in a Parturient Undergoing Cesarean Section , Journal of Society Medicine: Vol. 4 No. 11 (2025): November
Gunawan Wijaya Setiawan , A Review of Non-surgical Strategies for Managing Chronic Rhinosinusitis , Journal of Society Medicine: Vol. 4 No. 9 (2025): September
Krina Murti, Windy Juliandra , Sampe Tua, Breastfeeding and Its Protective Role Against Breast Cancer: A Meta-Analysis of Surgical and Non-Surgical Cases , Journal of Society Medicine: Vol. 4 No. 4 (2025): April
Antonius Leonardo Purba, Refli Hasan, Abdul Halim Raynaldo, The TIMI Risk Index as a Predictor of Contrast-Induced Nephropathy in Patients Undergoing Primary Percutaneous Coronary Intervention at Haji Adam Malik Hospital Medan , Journal of Society Medicine: Vol. 4 No. 3 (2025): March
Armansyah Maulana Harahap , Muhammad Aldi Rivai Ginting, Yulia Putri, Herviani Sari, Indra Priawan, Antidiabetic Effects of Moringa oleifera Leaf Extract on Blood Glucose Levels in Alloxan-Induced Diabetic Rats (Rattus norvegicus): A Systematic Literature Review , Journal of Society Medicine: Vol. 4 No. 12 (2025): December
Fadli Ilhami, Ali Nafiah Nasution, Cut Aryfa Andra, Prognostic Value of Tricuspid Annular Plane Systolic Excursion (TAPSE), Right Ventricular Fractional Area Changes (RV FAC) and Pulses Tissue Doppler S' Wave (PTD S') at 30 Days after Care of Acute Miocardial Infarction Patients in Haji Adam Malik Hospital , Journal of Society Medicine: Vol. 2 No. 5 (2023): May
Angela Yurika Purba, Syamsul Bihar, Bintang Y.M. Sinaga, Correlation Between Neutrophil to Lymphocyte Ratio (NLR) and Procalcitonin Levels in Sepsis Pneumonia Patients , Journal of Society Medicine: Vol. 3 No. 11 (2024): November
Bernadeth Bernadeth, Muchammad Erias Erlangga, Management of a Critically Ill Post-Cesarean Section Patient with Antepartum Hemorrhage Due to Placenta Previa Totalis in a G2P1A0 at 27–28 Weeks Gestation with Severe Preeclampsia, HELLP Syndrome, Pulmonary Edema, Stage 2 Acute Kidney Injury, and Hypoalbuminemia , Journal of Society Medicine: Vol. 4 No. 7 (2025): July
Marisa Heidiyana, Khairul Putra Surbakti, Haflin Soraya Hutagalung, The Association Between Degree of Severity and Number of Medications with Quality of Life in Parkinson's Disease Patients , Journal of Society Medicine: Vol. 2 No. 4 (2023): April

<< < 4 5 6 7 8 9 10 11 12 > >>

You may also start an advanced similarity search for this article.

PDF

Published at

12. January 2023
https://doi.org/10.47353/jsocmed.v2i1.26
Issue:

Vol. 2 No. 1 (2023): January
Section:

Articles
Keywords:

nutritional status acute ischemic stroke CONUT score type 2 diabetes mellitus
References:

Bender M, Jusufovic E, Railic V, Kelava S, Tinjak S, Dzevdetbegovic D, et al. High burden of stroke risk factors in developing country: the Case Study of Bosnia-Herzegovina. Mater Sociomed. 2017; 29(4):277-9.

Zhang FL, Guo ZN, Wu YH, Liu HY, Luo Y, Sun MS, et al. Prevalence of stroke and associated risk factors: a population based cross sectional study from northeast China. BMJ Open. 2017; 7(9):1-11.

Kementerian Kesehatan RI Badan Penelitian dan Pengembangan. Hasil utama riset kesehatan dasar Tahun 2018. Kementerian Kesehatan Republik Indonesia. 2018; 1–100.

Sacco RL, Kasner SE, Broderick JP, Caplan LR, Connors JJ, Culebras A, et al. An updated definition of stroke for the 21st Century: a statement for healthcare professionals from the American Heart Association/American Stroke Association. AHA Journals. 2013; 44(7):2064–89.

Tziomalos K, Dimitriou P, Bouziana SD, Spanou M, Kostaki S, Angelopoulou SM, et al. Stress hyperglycemia and acute ischemic stroke in hospital outcome. Metabolism Journal. 2017; 67:99–105.

Foley N, Teassel R, Marina R, Wiener J, Finestone H. Nutritional interventions following stroke. Neurorehabilitation and Neural Repair. 2018; 1–42.

Corrigan ML, Escuro AA, Celestin J, Kirby DF. Nutrition in the stroke patient. Nutrition in Clinical Practice. 2011; 26(3):242–52.

Shiga Y, Nezu T, Hosomi N, Aoki S, Nishi H, Naito H, et al. Effect of tooth loss and nutritional status on outcomes after ischemic stroke. Nutrition. 2019;5-14.

Çoban E. Malnutrition Rate in Stroke Patients on Admission. Med Bull Sisli Etfal Hosp. 2019; 53(3):272–275. doi: 10.14744/SEMB.2018;81994.

Naito H, Hosomi N, Nezu T, Kuzume D, Aoki S, Morimoto Y, et al. Prognostic role of the controlling nutritional status score in acute ischemic stroke among stroke subtypes. Journal of the Neurological Sciences. 2020;416:1-6.

Xiang W, Chen X, Ye W, Li J, Zhang X, Xie D. Prognostic nutritional index for predicting 3-month outcomes in ischemic stroke patients undergoing thrombolysis. Frontiers in Neurology. 2020; 11:1–7.

Cai ZM, Wu YZ, Chen HM, Feng RQ, Liao CW, Ye SL, et al. Being at risk of malnutrition predicts poor outcomes at 3 months in acute ischemic stroke patients. European Journal of Clinical Nutrition. 2020; 74(5):796–805.

Rambe AS, Fithrie A, Nasution I dan Tonam. Profil pasien stroke pada 25 rumah sakit di Sumatera Utara 2012 survei berbasis rumah sakit. Neurona. 2013;30(2).

Ritarwan K, Yenita Y. Nilai Prognostik Parameter Fibrinogen dan Uji Reliabilitas terhadap Outcome Stroke Iskemik Akut. 2017;2(2):11.

Nordström A, Hadrévi J, Olsson T, Franks PW, Nordström P. Higher Prevalence of Type 2 Diabetes in Men Than in Women Is Associated With Differences in Visceral Fat Mass. J Clin Endocrinol Metab. 2016;101(10):3740-3746. doi:10.1210/jc.2016-1915

Gibson CL. Cerebral Ischemic Stroke: is Gender Important?. J Cereb Blood Flow Metab. 2013;33(9):1355–61.

Pranata H, Sinurat PPO, Batubara CA. Hubungan Rasio Neutrofil Limfosit dan High Sensitivity C-Reactive Protein Dengan Keparahan Dan Outcome Pada Pasien Stroke Iskemik Akut. Universitas Sumatera Utara. 2022.

Apriani N, Sinurat PPO, Kadri A. Changes in platelet aggregation and nihss after anti-platelet therapy for acute ischemic stroke patients at H.Adam Malik General Hospital Medan. IJRSM. 2020;7(8):45–50.

Yousufuddin M, Young N. Aging and ischemic stroke. Aging. 2019 (9):2542–4.

Barus LI, Fithrie A, Batubara CA. Perbandingan Asupan Nutrisi dan Keparahan pada Pasien Stroke Iskemik Akut dengan dan Tanpa Pemberian Suplementasi Nutrisi Oral. Tesis. Universitas Sumatera Utara. 2021.

Patibandla S, Appikatla T, Jayasingh K. Study of the severity of stroke at the time of presentation in diabetic patients correlating with glycemic control. Int J Adv Med. 2017;4(2):396-400.

Das PP. Glycemic status in acute stroke in relation to its severity and outcome. Journal of Medical Science and clinical Research. 2019;7(3):1122– 30.

Manickam S, Franklin J, Petchiappan V, Menon S. A Study of Serum Albumin Levels in Acute Ischemic Stroke and its Correlation with Clinical Outcome. IJCMR. 2019;6(3).

Kasundra G, Sood I. Prognostic Significance Of Serum Albumin Levels In Acute Ischemic Stroke. 2014; 5(4).

Nair R, Radhakrishnan K, Chatterjee A, Gorthi SP, Prabhu VA. Serum Albumin as a Predictor of Functional Outcomes Following Acute Ischemic Stroke. 2018; 10(4).

Koton S, Molshatzki N, Bornstein NM, Tanne D, on behalf of the NASIS Investigators. Low Cholesterol, Statins and Outcomes in Patients with First- Ever Acute Ischemic Stroke. Cerebrovasc Dis. 2012 ;34(3):213–20.

Markaki I, Nilsson U, Kostulas K, Sjöstrand C. High Cholesterol Levels Are Associated with Improved Long-term Survival after Acute Ischemic Stroke. Journal of Stroke and Cerebrovascular Diseases. 2014 ;23(1):e47–53.

Juli C, Heryaman H, Nazir A, Ang E-T, Defi IR, Gamayani U, et al. The Lymphocyte Depletion in Patients with Acute Ischemic Stroke Associated with Poor Neurologic Outcome. International Journal of General Medicine. 2021; 4:1843–51.

Akimoto T, Hara M, Morita A, Uehara S, Nakajima H. Relationship between Nutritional Scales and Prognosis in Elderly Patients after Acute Ischemic Stroke: Comparison of Controlling Nutritional Status Score and Geriatric Nutritional Risk Index. Ann Nutr Metab. 2021 ;77(2):116–23.

López Espuela F, Roncero-Martín R, Zamorano JDP, Rey-Sanchez P, Aliaga- Vera I, Portilla Cuenca JC, et al. Controlling Nutritional Status (CONUT) Score as a Predictor of All-Cause Mortality at 3 Months in Stroke Patients. Biological Research For Nursing. 2019 ;21(5):564–70.
Share:

Z

Chaniago, S. A. S., Nasution, I., & Nasution, I. K. (2023). The Association of Nutrition Status Towards The Outcome of Acute Ischemic Stroke Patients with Type-2 Diabetes Mellitus. Journal of Society Medicine, 2(1), 14–23. https://doi.org/10.47353/jsocmed.v2i1.26