Effect of Glycemic Parameters on Mortality of Type 2 Diabetes Mellitus Patients with COVID-19 Infection in Haji Adam Malik Hospital Medan

Jessica Patricia Pangaribuan; Santi Syafril; Dian Anindita Lubis; Rahmad Isnanta; Imelda Rey

doi:10.47353/jsocmed.v2i8.81

Effect of Glycemic Parameters on Mortality of Type 2 Diabetes Mellitus Patients with COVID-19 Infection in Haji Adam Malik Hospital Medan

Jessica Patricia Pangaribuan
Master of Clinical Medicine, Internal Medicine Department, Faculty of Medicine, Sumatera Utara University, Medan, Indonesia
Santi Syafril
Department of Internal Medicine, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia
Dian Anindita Lubis
Department of Internal Medicine, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia
Rahmad Isnanta
Department of Internal Medicine, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia
Imelda Rey
Department of Internal Medicine, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia

Abstract

Introduction: Diabetes Mellitus Type 2 (DM T2) is a major health problem, especially in people in developing countries. DM T2 is the most frequently reported comorbid disease in patients with COVID-19. The relationship between DM T2 and poorer outcome in COVID-19 infection is thought to be because hyperglycemia and chronic inflammation impair control of viremia and inflammation by weakening the immune response. This research aim to determine the effect of glycemic parameters on the mortality of DM T2 patients with COVID-19.

Method: This research is a descriptive analytic study with a retrospective design which was carried out at the H. Adam Malik General Hospital in Medan. The data obtained was analyzed statistically and said to be statistically significant if p <0.05.

Results: Based on the results of the study, there were significant differences in the values of inflammatory markers such as leukocytes, neutrophils, NLR, PCT, LDH, D-dimer, ferritin, SGOT, urea and creatinine in the severity of COVID-19 patients and there were significant differences in the mean fasting blood sugar, blood sugar 2PP, in moderate, severe and critical COVID-19 patients.

Conclusion: Glycemic parameters in patients who died were worse than patients who recovered, although the statistical results were not significantly different.

Similar Articles

Grace Nikensari, Ali Nafiah Nasution, Abdullah Afif Siregar, Monocyte to High-Density Lipoprotein Ratio (MHR) as A Predictor of Major Cardiovascular Events in Acute Myocardial Infarction Patients with ST-Segment Elevation in Patients Undergoing Primary Percutaneous Coronary Intervention at Haji Adam Malik Central General Hospital , Journal of Society Medicine: Vol. 3 No. 5 (2024): May
Amirra Fairuz SMW, Tubagus Ferdi Fadilah, Maternal Knowledge of Exclusive Breastfeeding and Nutritional Status of Children Under Two Years During the COVID-19 Pandemic , Journal of Society Medicine: Vol. 4 No. 1 (2025): January
Putri Nahrisyah, Fajrinur Syahrani, Amira Permatasari Tarigan, Taufik Ashar, Survival Rate of Chronic Obstructive Pulmonary Disease Patients with Type II Respiratory Failure at Haji Adam Malik Hospital , Journal of Society Medicine: Vol. 3 No. 8 (2024): August
Cut Putri Hazlianda, Dina Arwina Dalimunthe, Awalia Astarina, Generalized Exfoliative Dermatitis Suspected Caused by COVID-19 Vaccine : A Case Report , Journal of Society Medicine: Vol. 2 No. 12 (2023): December
Rizka Farahin Assania, Elvita Rahmi Daulay, Refli Hasan, Association of Risk Factors for Coronary Artery Disease with The Incidence of Abdominal Aortic Calcification On Abdominal CT-Scan Imaging in H. Adam Malik General Hospital , Journal of Society Medicine: Vol. 2 No. 3 (2023): March
Harel Mega Serafine Simanjuntak, Haflin Soraya Hutagalung, Indri Adriztina, Sri Amelia, Relationship Between Sleep Quality and Primary Headache Among Employees of PT. Valeo Ac Indonesia , Journal of Society Medicine: Vol. 3 No. 12 (2024): December
Nengah Darmawan, Amira Permatasari Tarigan, Andika Pradana, Relationship Between Asthma Therapy Types, Pulmonary Function, and Asthma Control in Primary Healthcare Facilities in Medan , Journal of Society Medicine: Vol. 4 No. 2 (2025): February
Yovita Belva Lokman, Dedy Dwi Putra, Setia Putra Tarigan, Ririe Fachrina Malisie, Thoracic CT Scan Image in Transudate and Exudate Pleural Effusion Cases at Haji Adam Malik General Hospital Medan in January - September 2024 , Journal of Society Medicine: Vol. 3 No. 12 (2024): December
Abdurrahman Asysyarif, Elvita Rahmi Daulay, Kiking Ritarwan, Correlation of Lacunar Infarct on Head Ct Scan with Dysarthria in Haji Adam Malik General Hospital in 2019 , Journal of Society Medicine: Vol. 2 No. 1 (2023): January
Army Zaka Anwary, Indriasari, Role of CRRT (Continuous Renal Replacement Therapy) as Management of Cardiac Arrest Patient with Postpartum Acute Lung Edema and Cardiomyopathy in the ICU , Journal of Society Medicine: Vol. 2 No. 6 (2023): June

<< < 1 2 3 4 > >>

You may also start an advanced similarity search for this article.

PDF

Published at

31. August 2023
https://doi.org/10.47353/jsocmed.v2i8.81
Issue:

Vol. 2 No. 8 (2023): August
Section:

Articles
Keywords:

Glycemic parameters COVID-19 Diabetes Mellitus type 2
References:

Milibari A, Matuure E, and Gadah E. Prevalence, Determinants and Prevention of Type 2 DM ( T2DM ) in Arabic Countries : A Ehab Y Matuure Systematic Review. Heal Sci J. 2020;14(2):1-8.

International Diabetes Federation. 2019. DM T2 Atlas 9th Edition 2019. Retrieved from www.DM T2atlas.org.

Riset Kesehatan Dasar (Riskesdas). 2018. Badan Penelitian dan Pengembangan Kesehatan Kementrian RI tahun 2018.

Serbis A, Giapros V, and Kotanidou E. Diagnosis, treatment and prevention of type 2 Diabetes melitus in children and adolescents Anastasios. World J DM T2. 2021;9358(4):1-10.

Guan WJ, Ni ZY, Hu Y, Liang WH, Ou CQ, He JX, et al. China Medical Treatment Expert Group for COVID-19. Clinical characteristics of coronavirus disease 2019 in China. N Engl J Med.2020;382:1708–1720 .

Parasher A. COVID-19 : Current understanding of its pathophysiology , clinical presentation and treatment. Postgr Med J. 2021;97:312-320.

Kumar B, Mittal M, Gopalakrishnan M, Garg MK, Misra S. Effect of plasma glucose at admission on COVID-19 mortality: experience from a tertiary hospital. Endocrine Connections. 2021;10: 589–598

Ilias I, Diamantopoulos A, Pratikaki M, Botoula E, Jahaj E, Athanasiou N, et al. Glycemia , Beta-Cell Function and Sensitivity to Insulin in Mildly to Critically Ill COVID-19 Patients. Medicina (B Aires). 2021;2:10-15.

Ghosh A, Mohan R, Subramanian C, and Rani S. Glycemic parameters in patients with new-onset DM T2 during COVID-19 pandemic are more severe than in patients with new-onset DM T2 before the pandemic: NOD COVID-19 India Study. DM T2 Metab Syndr Clin Res Rev. 2020;22:1-10.

Verma AK, Beg M, Bhatt D, Dev K, Alsahli M, Rahmani A, Goyal Y. Assessment and Management of Diabetic Patients During the COVID-19 Pandemic. DM T2, Metabolic Syndrome and Obesity: Targets and Therapy. 2021;14:3131–3146.

Pieralli F, Pomero F, Giampieri M, Marcucci R, Prisco D, Luise F, et al. Incidence of deep vein thrombosis through an ultrasound surveillance protocol in patients with COVID-19 pneumonia in non-ICU setting: A multicenter prospective study. PLoS ONE. 2021;16(5):e0251966.

Kumar B, Mittal M, Gopalakrishnan M, Garg MK, Misra S. Effect of plasma glucose at admission on COVID-19 mortality: experience from a tertiary hospital. Endocrine Connections. 2021;10:589–598.

Tanji Y, Sawada S, Watanabe T, Mita T, Kobayashi Y, Murakami T, et al. Impact of COVID-19 pandemic on glycemic control among outpatients with type 2 DM T2 in Japan: A hospital-based survey from a country without lockdown. DM T2 Research and Clinical Practice. 2021;176: 108840.

Ginting PK, Syafril S. Association Between Blood Glucose Profiles with Severity of COVID-19 and Type 2 DM T2 Patients. Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI). 2022;4(2): 56-61.

Patel AJ, Klek SP, Peragallo-dittko V, Goldstein M, Burdgr E, Nadile V, Ramadhar J, Islam S, Rothberger GD. Correlation of Hemoglobin A1C and Outcomes in Patients Hospitalized With COVID-19 . Elsevier. 2020.
Share:

Z

Pangaribuan, J. P., Syafril, S., Lubis, D. A., Isnanta, R., & Rey, I. (2023). Effect of Glycemic Parameters on Mortality of Type 2 Diabetes Mellitus Patients with COVID-19 Infection in Haji Adam Malik Hospital Medan. Journal of Society Medicine, 2(8), 283–289. https://doi.org/10.47353/jsocmed.v2i8.81